F. K. Mardakheh

This paper identifies JUNI, a stress-induced lncRNA critical for cancer cell survival, and shows its interactome predicts prognosis in clear cell renal cell carcinoma.

TREX identifies RNA-binding proteins interacting with specific RNA regions in living cells, revealing novel interactions in 45S rRNA and U1 snRNA.

The paper identifies JUNI as a lincRNA essential for cancer cell survival and patient prognosis, showing its role in regulating c-Jun and interacting with DUSP14.

This study identifies Nucleolin as a key mediator of RAS-driven ribosome biogenesis and tumorigenesis through enhanced RNA-binding activity.

This paper identifies PF-477736 as a selective cytotoxic compound for LIMD1-deficient NSCLC cells and xenograft models, offering a potential targeted therapy for this understudied cancer subtype.

The paper shows centrosome amplification in pancreatic cancer cells increases small extracellular vesicle secretion through lysosomal dysfunction, promoting tumor invasion.

The paper shows that subcellular localization of RP-mRNAs via LARP6 enhances ribosome biogenesis during cell migration and supports cancer progression through EMT.