An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
M. S. Azman, M. Dodel, F. Capraro, R. Faraway, M. Dermit, W. Fan, J. Ule, F. K. Mardakheh
This study identifies Nucleolin as a key mediator of RAS-driven ribosome biogenesis and tumorigenesis through enhanced RNA-binding activity.
bioRxiv · Dec 16, 2021Cancer Biology