Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function
K. E. Leon, R. E. Flynn, M. M. Khalid, K. A. Fontaine, T. Nguyen, R. Kumar, C. R. Simoneau, S. Tomar, D. Jimenez-Morales, M. Dunlap, J. A. Kaye, P. S. Shah, S. Finkbeiner, N. J. Krogan, C. Bertozzi, , M. Ott
This study shows ZIKV infection disrupts UPF1 function, leading to nuclear mRNA accumulation and impaired neural progenitor cell function.
bioRxiv · Dec 3, 2020 · PreprintMicrobiology