P. S. Shah

The paper evaluates light propagation in cylindrical bioreactors to determine the scalability of optogenetic control in mammalian cell cultures.

This study identifies Hippo signaling pathway activation as an antiviral response to SARS-CoV-2 infection and shows pharmacological targeting of the pathway can reduce virus replication.

The paper improves Spike protein expression in CHO cells by developing truncations that outperform full-length Spike and RBD in expression levels and antibody binding.

This paper shows that DENV NS5 interacts with PAF1C to suppress immune response genes, and disrupting this interaction restores PAF1-dependent gene expression.

This study shows ZIKV infection disrupts UPF1 function, leading to nuclear mRNA accumulation and impaired neural progenitor cell function.

This study evaluates light-activated gene expression in CHO cells using optogenetics, showing transient activation but limited stable expression.

This study shows that ZIKV infection disrupts the NMD pathway by interacting with UPF1 via its capsid protein, enhancing viral infection and contributing to neuropathology.