Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
R. Winkler, A.-S. Mägdefrau, E.-M. Piskor, M. Kleemann, M. Beyer, K. Linke, L. Hansen, A.-M. Schaffer, M. E. Hoffmann, S. Poepsel, F. Heyd, P. Beli, T. Möröy, S. Mahboobi, O. H. Krämer, C. Kosan
This study shows that inhibiting HDAC6 with Marbostat-100 reduces MYC levels and prevents lymphomagenesis in a mouse model of MYC-induced B-cell lymphoma.
Oncogene · Sep 6, 2022Peer-reviewedCancer Biology