Single-cell multimodal glioma analyses reveal epigenetic regulators of cellular plasticity and environmental stress response
K. C. Johnson, K. J. Anderson, E. T. Courtois, F. Barthel, F. S. Varn, D. Luo, M. Seignon, E. Yi, H. Kim, M. Estecio, M. Tang, N. Navin, R. Maurya, C. Ngan, N. Verburg, , R. Verhaak
The paper integrates multi-omic data from gliomas to show that epigenetic instability and transcriptional disruption are linked to tumor aggressiveness and environmental stress response.
bioRxiv · Jul 22, 2020Cancer Biology