Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands
Z. Lyu, X. Lyu, G. Xia, D. Carney, V. M. Alves, M. Falk, N. Arora, H. Zou, A. McGrath, Y. Kang
This study presents structural insights into PAR1 and PAR2 activation by endogenous ligands, revealing a novel mechanism and potential targets for therapeutic development.
bioRxiv · Jul 8, 2024 · PreprintBiochemistry