Author

M. Rosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Mey· 1 shared A. Pandini· 1 shared A. Pearce· 1 shared A. Ramanathan· 1 shared B. Islam· 1 shared D. BHOWMIK· 1 shared D. Kubli· 1 shared D. Safitri· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiophysics

A. Mey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer-Associated Mutations Enhance The Sensitivity Of The Trupath GαQ/11 System

D. Safitri, M. Harris, A. Pearce, X. Huang, M. Rosa, K. Barkan, E. Wills, M. Marti-Solano, M. Falk, G. Ladds

The paper modifies Gq and G11 biosensors to enhance sensitivity for detecting Gq/11 activation in GPCRs, including those with cancer-associated mutations.

bioRxiv · Sep 1, 2022 · PreprintPharmacology & Toxicology

Breast Cancer Reaction-Diffusion from Spectral-Spatial Analysis in Immunohistochemistry

S. Pasetto, M. U. Zahid, R. Diaz, M. Montejo, M. Rosa, R. Gatenby, H. Enderling

The paper uses spatial-spectral analysis of immunohistochemistry data to model tumor growth dynamics via reaction-diffusion equations in breast cancer patients.

bioRxiv · Jul 10, 2022 · PreprintCancer Biology

Structural dynamics of the β-coronavirus Mpro protease ligand binding sites

E. Cho, M. Rosa, R. Anjum, S. Mehmood, M. Soban, M. Mujtaba, K. Bux, S. C. Dantu, A. Pandini, J. Yin, H. Ma, A. Ramanathan, B. Islam, A. Mey, D. BHOWMIK, S. Haider

The paper compares ligand-binding sites of Mpro proteases from SARS-CoV2, SARS-CoV, and MERS-CoV using deep learning and Markov state models to assess structural dynamics and conservation.

bioRxiv · Mar 31, 2021 · PreprintBiophysics

Tetraploidy in rodent cardiac stem cells confers enhanced biological properties

K. Broughton, T. Khieu, N. Nguyen, M. Rosa, S. Mohsin, P. Quijada, J. Wang, O. Echeagaray, D. Kubli, T. Kim, F. Firouzi, M. Monsanto, N. Gude, R. Adamson, W. Dembitsky, , M. Sussman

The paper compares ploidy in cardiac interstitial cells between rodents and large mammals, finding species-specific differences in tetraploidy and its functional implications.

bioRxiv · Mar 26, 2019 · PreprintCell Biology