A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation
C. E. Mackay, M. Floen, M. D. Leo, R. Hasan, C. Fernandez-Pena, P. Singh, K. U. Malik, J. H. Jaggar
This study shows that PC-1 and PC-2 form a complex in endothelial cells that mediates flow-induced vasodilation through Ca2+ influx and NOS activation.
bioRxiv · Oct 16, 2021Physiology