Cancer BiologybioRxiv
YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics
P.-D. Fan, G. Narzisi, A. D. Jayaprakash…·M. Ladanyi
This study identifies YES1 amplification as a novel mechanism of resistance to EGFR inhibitors in lung cancer using transposon mutagenesis and clinical genomic analysis.
DOI 10.1073/pnas.1717782115