Author

M. Gerlic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

H. Cohen· 5 shared D. Salomon· 4 shared L. Edry-Botzer· 3 shared N. Baram· 2 shared A. Munitz· 1 shared B. Ushijima· 1 shared C. M. Fridman· 1 shared E. Bosis· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

H. Cohen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A T6SS in the coral pathogen Vibrio coralliilyticus secretes an arsenal of anti-eukaryotic effectors and contributes to virulence

S. Mass, H. Cohen, M. Gerlic, B. Ushijima, J. C. van Kessel, E. Bosis, D. Salomon

This study identifies two temperature-regulated T6SSs in Vibrio coralliilyticus, revealing their roles in bacterial competition and host toxicity, with T6SS2 secreting nine novel anti-eukaryotic toxins.

bioRxiv · Mar 20, 2024Microbiology

Engineering a genetic system for female-biased, genetically unmodified progeny in mice without affecting litter size

I. Yosef, T. Mahata, X. Xie, Y. Chen, H. Bar-Joseph, Q.-Y. Sun, R. Shalgi, A. Munitz, M. Gerlic, U. Qimron

The paper describes a genetic system in mice that produces predominantly female offspring without affecting litter size or introducing genetic modifications into the offspring.

bioRxiv · Nov 21, 2023 · PreprintBioengineering

A Vibrio T6SS-mediated lethality in a marine animal model

H. Cohen, M. Gerlic, D. Salomon

This study shows Vibrio proteolyticus uses T6SS3 to kill Artemia salina, identifying two known and one novel effector contributing to host lethality.

bioRxiv · Mar 6, 2023Microbiology

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

H. Cohen, N. Baram, C. M. Fridman, L. Edry-Botzer, D. Salomon, M. Gerlic

The paper identifies two novel T6SS effectors from Vibrio that induce pyroptosis via NLRP3 inflammasome activation in mammalian immune cells and reveal a compensatory pathway.

bioRxiv · Aug 11, 2022Immunology

Proteomic analysis of necroptotic extracellular vesicles

I. Shlomovitz, G. Yanovich-Arad, Z. Erlich, L. Edry-Botzer, S. Zargarian, H. Cohen, Y. Ofir-Birin, N. Regev-Rudzki, M. Gerlic

The paper identifies the protein composition of necroptotic extracellular vesicles and shows their role in modulating immune responses and antigen presentation.

bioRxiv · Apr 11, 2020Cell Biology

Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

N. Baram, H. Cohen, L. Edry-Botzer, D. Salomon, M. Gerlic

This study shows that VPRH, a Vibrio leukocidin, induces pyroptotic cell death via NLRP3 inflammasome activation in macrophages, with a second unknown mechanism.

bioRxiv · Oct 24, 2019Immunology