Author

M. Grashoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:virus· 1

Frequent Co-Authors

A. Kroeger· 2 shared K. Eschke· 2 shared L. Brunotte· 2 shared L. Cicin-Sain· 2 shared S. Ludwig· 2 shared Y. Kim· 2 shared D. Meier· 1 shared D. Schaeckermann· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Kroeger

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

M. Z. Chaudhry, K. Eschke, M. Hoffmann, M. Grashoff, L. Abassi, Y. Kim, L. Brunotte, S. Ludwig, A. Kroeger, F. Klawonn, S. Pöhlmann, L. Cicin-Sain

This study shows SARS-CoV-2 adapts to Vero E6 cells by losing the furin cleavage motif in spike protein, but retains wildtype sequences, enabling reverse adaptation when passaged on human lung cells.

bioRxiv · Aug 10, 2020Microbiology

SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

F. Bertoglio, D. Meier, N. Langreder, S. Steinke, U. Rand, L. Simonelli, P. A. Heine, R. Ballmann, K.-T. Schneider, K. D. R. Roth, M. Ruschig, P. Riese, K. Eschke, Y. Kim, D. Schaeckermann, , M. Hust

The paper identifies potent SARS-CoV-2 neutralizing antibodies from pre-pandemic human donors that bind the RBD-ACE2 interface, showing high neutralization efficacy in vitro.

bioRxiv · Jun 5, 2020Biochemistry