An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
m. Harmse, M. M. Habib, S. Nemska, A. Nicolo, A. Gilg, N. Preising, P. Sokkar, S. Carmignani, M. Raasholm, G. Weidinger, G. Kizilsavas, M. Wagner, L. Staendker, A. M. Abadi, H. Jumaa, , J. Muench
The paper develops an optimized CXCR4 antagonist, JM#21, which effectively prevents atopic dermatitis and airway inflammation in mouse models.
bioRxiv · Aug 28, 2020Immunology