ImmunologybioRxiv
THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS
A. G. Kay, K. Treadwell, P. Roach…·O. Kehoe
This study evaluates the therapeutic effects of hypoxically and pro-inflammatory primed MSC-derived EVs in inflammatory arthritis, finding normoxic EVs most effective in reducing joint swelling and improving histopathology.
DOI 10.3390/ijms23010126