Author

M. Imoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Saiki· 2 shared A. Acharjee· 1 shared A. Sanz· 1 shared A. Suzuki· 1 shared B. Carroll· 1 shared C. Bascom· 1 shared D. Shapira· 1 shared E. G. Otten· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

S. Saiki

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Identification of novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease

Y. Date, Y. Sasazawa, M. Kitagawa, K. Gejima, A. Suzuki, H. Saya, M. Imoto, E. Itakura, N. Hattori, S. Saiki

This study identifies six drugs that enhance autophagy by promoting lysosomal clustering, which facilitates the degradation of protein aggregates associated with Parkinson's disease.

bioRxiv · Nov 7, 2023Cell Biology

Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

L. Sedlackova, E. G. Otten, F. Scialo, D. Shapira, T. Kataura, B. Carroll, E. Seranova, Y. Rabanal Ruiz, G. Kelly, R. Stefanatos, G. Nelson, F. Urselli, A. Acharjee, N. S. Kenneth, S. A. Trushin, , V. I. Korolchuk

This study identifies autophagy's role in maintaining NAD(H) pools, showing that NAD(H) depletion leads to cell death and that NAD(H) supplementation can reverse this effect in autophagy-deficient models.

bioRxiv · Jan 31, 2020 · PreprintCell Biology