M. Inada

Binding of cardiolipin to the KcsA channel at the membrane outer leaflet allosterically opens the inner gate

The paper shows cardiolipin binding to KcsA's outer leaflet triggers an allosteric opening of the inner gate via interactions with Arg64 and Arg89.

An SNP variant MT1-MMP with a defect in its collagenolytic activity confers the fibrotic phenotype of Dupuytren's Disease

This study identifies an SNP variant in MMP14 that reduces collagenolytic activity, contributing to the fibrotic phenotype of Dupuytren's Disease.