N. Sato

Endoplasmic reticulum stress signaling actively contributes to therapy resistance in colorectal cancer

This study investigates how ER stress signaling contributes to therapy resistance in colorectal cancer by analyzing genomic alterations and testing therapeutic responses in cell lines and organoids.

Connection between drug-mediated neurotransmission and salivary microbiome

This study investigates how CNS drugs affect the salivary microbiome and links these changes to cognitive function and neurodegeneration.

Acyl plastoquinol is a major substance that co-migrates with triacylglycerol in cyanobacteria

The paper identifies acyl plastoquinol as a major compound co-migrating with triacylglycerol in cyanobacteria, but finds no clear evidence for triacylglycerol's presence.

Zinc-finger protein 518 plays a crucial role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin

This study identifies ZNF518's role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin through interactions with CENP-B, HP1, and G9a.

Genome analysis of Parmales, a sister group of diatoms, reveals the evolutionary specialization of diatoms from phago-mixotrophs to photoautotrophs

This study compares parmalean and diatom genomes to show diatoms evolved from phago-mixotrophs to photoautotrophs by losing phagocytosis genes and gaining silica and nutrient metabolism capabilities.

Orchestration of Proteins in cyanobacterial Circadian Clock System 1

This study reveals that the cyanobacterial circadian clock involves synchronized multiple association-dissociation reactions between Kai proteins, not a single process as previously thought.

Design, development, and preliminary assessment of a novel peripheral intravenous catheter aimed at reducing early failure rates

This paper designs a novel peripheral intravenous catheter (FloRamp) to reduce early failure rates and reports preliminary results from animal testing showing reduced occlusion and lower phlebitis scores.

Action selection based on multiple-stimulus aspects in the wind-elicited escape behavior of crickets

This study investigates how crickets select between running and jumping escape responses based on airflow stimulus parameters, finding that velocity and duration influence response choice and movement characteristics.

Independent adoptions of a set of proteins found in the matrix of the mineralized shell-like eggcase of Argonaut octopuses

This study identifies that Argonaut octopuses use a distinct set of proteins to form their shell-like eggcase, which is not homologous to the shells of other mollusks.

Sense of absence: Spatial perception through active sensing by insect antennal mechanosensory system

This study shows crickets use active antennal sensing to perceive object presence and absence, adjusting escape behavior to avoid collisions.

Helping Behavior in Prairie Voles: A Model of Empathy and the Importance of Oxytocin

This study shows prairie voles learn to help distressed conspecifics by opening a door, and oxytocin is necessary for this behavior, with no sex differences observed.

Context-dependent behavioral plasticity compromises disruptive selection on sperm traits in squid

The paper investigates how context-dependent behavioral plasticity affects the development of alternative sperm traits in squid, showing that social contexts influence sperm morphology and mating strategies.

An SNP variant MT1-MMP with a defect in its collagenolytic activity confers the fibrotic phenotype of Dupuytren's Disease

This study identifies an SNP variant in MMP14 that reduces collagenolytic activity, contributing to the fibrotic phenotype of Dupuytren's Disease.

Polyandry is extremely rare in the firefly squid, Watasenia scintillans

The paper provides empirical evidence for monogamy in the firefly squid, Watasenia scintillans, showing that most females store spermatangia from a single male and all embryos are sired by that male.

The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A

This study identifies the InvX region of M.leprae's mce1A protein as critical for epithelial cell entry, distinct from the InvIII region in M.tuberculosis.