Author

M. Ingelman-Sundberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

B. A. L. M. Deiman· 1 shared E. Jarvinen· 1 shared H. S. Hammer· 1 shared H.-J. Guchelaar· 1 shared I. Johansson· 1 shared J. J. Swen· 1 shared M. J. Deenen· 1 shared M. van der Lee· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. A. L. M. Deiman

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivOct 30, 2022

3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction

E. Jarvinen, H. S. Hammer, O. Potz…·T. B. Stage

This study evaluates 3D spheroid primary human hepatocytes as a model to assess induction of CYP enzymes and drug transporters, showing strong correlation with clinical findings.

DOI 10.1002/cpt.2887

humanbulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivMar 2, 2020

A unifying model to predict variable drug response for personalised medicine

M. van der Lee, W. G. Allard, R. H. A. M. Vossen…·S. Y. Anvar

The paper introduces a continuous scale model using full gene sequencing and neural networks to predict CYP2D6 enzyme activity, explaining 79% of interindividual variability in drug response.

DOI 10.1126/scitranslmed.abf3637

humanwhole-exome sequencing

𝕏 PostBluesky