Author

M. J. Griffiths

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

T. Solomon· 2 shared A. Brown· 1 shared A. J. Pollard· 1 shared A. Trebes· 1 shared B. Lee· 1 shared C. Goh· 1 shared C. J. Hinds· 1 shared D. Bonsall· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

T. Solomon

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Author profile →

2 papers

Recent·Most cited

Targeted metagenomic sequencing enhances the identification of pathogens associated with acute infection.

C. Goh, T. Golubchik, M. A. Ansari, M. de Cesare, A. Trebes, I. Elliott, D. Bonsall, P. Piazza, A. Brown, H. Slawinski, N. Martin, S. Defres, M. J. Griffiths, J. E. Bray, M. C. Maiden, , R. Bowden

Castanet, a targeted metagenomic sequencing method, improves pathogen detection in clinical samples by combining sensitivity with cost-effectiveness and broad organism coverage.

bioRxiv · Jul 28, 2019 · PreprintMicrobiology

TREM-1 activation is a key regulator in driving severe pathogenesis of enterovirus 71 infection

S. N. Amrun, J. J. Tan, N. Y. Rickett, J. A. Cox, B. Lee, M. J. Griffiths, T. Solomon, D. Perera, M. H. Ooi, J. A. Hiscox, L. F. Ng

The paper investigates EV71 infection in human cells, identifies TREM-1 activation as a key driver of severe disease, and shows its role in inflammation and viral load.

bioRxiv · Jun 27, 2019Immunology