Lipid hydroperoxides promote sarcopenia through carbonyl stress
H. Eshima, J. L. Shahtout, P. Siripoksup, M. J. Pearson, Z. S. Mahmassani, P. J. Ferrara, A. W. Lyons, J. A. Maschek, A. D. Peterlin, A. R. P. Verkerke, J. M. Johnson, A. Salcedo, J. J. Petrocelli, E. R. Miranda, E. J. Anderson, , K. Funai
This study shows lipid hydroperoxides contribute to sarcopenia by causing carbonyl stress, and their neutralization prevents muscle atrophy and weakness.
bioRxiv · Dec 17, 2021Physiology