Author
H. Eshima
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 44 mutual co-author links5 papers
Recent·Most cited
Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity
J. L. Shahtout, H. Eshima, P. J. Ferrara, J. A. Maschek, J. E. Cox, M. J. Drummond, K. Funai
This study shows that inhibiting the Lands cycle in skeletal muscle reduces lipid hydroperoxide levels, protecting against disuse-induced atrophy and weakness in mice.
bioRxiv · Jul 25, 2023Physiology
Phosphatidylethanolamine facilitates mitochondrial pyruvate entry to regulate metabolic flexibility
P. Siripoksup, G. Cao, A. A. A. Cluntun, J. A. Maschek, Q. Pearce, M. J. Lang, H. Eshima, P. C. Opurum, Z. S. Mahmassani, E. B. Taylor, J. E. Cox, M. J. Drummond, J. Rutter, K. Funai
This study identifies phosphatidylethanolamine's role in regulating mitochondrial pyruvate entry, linking it to metabolic flexibility in skeletal muscle.
bioRxiv · Nov 1, 2022 · PreprintPhysiology
Lipid hydroperoxides promote sarcopenia through carbonyl stress
H. Eshima, J. L. Shahtout, P. Siripoksup, M. J. Pearson, Z. S. Mahmassani, P. J. Ferrara, A. W. Lyons, J. A. Maschek, A. D. Peterlin, A. R. P. Verkerke, J. M. Johnson, A. Salcedo, J. J. Petrocelli, E. R. Miranda, E. J. Anderson, , K. Funai
This study shows lipid hydroperoxides contribute to sarcopenia by causing carbonyl stress, and their neutralization prevents muscle atrophy and weakness.
bioRxiv · Dec 17, 2021Physiology
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
T. D. Heden, J. M. Johnson, P. J. Ferrara, H. Eshima, A. R. Verkerke, E. J. Wentzler, P. Siripoksup, T. M. Narowski, C. B. Coleman, C.-T. Lin, T. E. Ryan, P. T. Reidy, L. E. de Castro Bras, C. M. Karner, C. F. Burant, , K. Funai
The paper shows that mitochondrial phospholipids, specifically phosphatidylethanolamine (PE), regulate respiratory capacity in skeletal muscle, with PE deficiency causing respiratory failure and oxidative stress.
bioRxiv · Apr 9, 2019Physiology