Mapping morphological malformation to genetic dysfunction in blood vessel organoids with 22q11.2 Deletion Syndrome
S. He, C. Xu, Y.-H. Lao, S. Chauhan, Y. Xiao, M. J. Willner, Y. Jin, S. McElroy, S. Rao, J. Gogos, R. Tomer, E. Azizi, B. Xu, K. W. Leong
This study uses blood vessel organoids from 22q11.2 DS patients to link genetic dysfunction to vascular malformations through single-cell transcriptomics and imaging.
bioRxiv · Nov 17, 2021 · PreprintBioengineering