Author

E. Azizi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 4 Research Focus:cell-cell communication· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

B. Xu· 2 shared C. Xu· 2 shared D. Pe'er· 2 shared K. W. Leong· 2 shared R. Tomer· 2 shared S. Chauhan· 2 shared S. He· 2 shared S. McElroy· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

B. Xu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy

K. Maurer, C. Park, S. Mani, M. Borji, L. Penter, Y. Jin, J. Y. Zhang, C. Shin, J. R. Brenner, J. Southard, S. Krishna, W. Lu, H. Lyu, D. Abbondanza, C. Mangum, , E. Azizi

The paper analyzes single-cell data from bone marrow samples to identify immune cell interactions that predict response to adoptive cellular therapy in myeloid leukemia.

bioRxiv · Feb 9, 2024 · PreprintCancer Biology

Human vascular organoids with a mosaic AKT1 mutation recapitulate Proteus syndrome

S. He, Y. Zhu, S. Chauhan, D. N. Tavakol, J. H. Lee, R. B.-L. Berris, C. Xu, J. Lee, C. Lee, S. Cai, S. McElroy, G. Vunjak-Novakovic, R. Tomer, E. Azizi, B. Xu, , K. W. Leong

This paper creates a vascular organoid model with an AKT1 mutation to study Proteus syndrome and finds AKT inhibitors reverse vascular malformations.

bioRxiv · Jan 26, 2024 · PreprintBioengineering

Mapping morphological malformation to genetic dysfunction in blood vessel organoids with 22q11.2 Deletion Syndrome

S. He, C. Xu, Y.-H. Lao, S. Chauhan, Y. Xiao, M. J. Willner, Y. Jin, S. McElroy, S. Rao, J. Gogos, R. Tomer, E. Azizi, B. Xu, K. W. Leong

This study uses blood vessel organoids from 22q11.2 DS patients to link genetic dysfunction to vascular malformations through single-cell transcriptomics and imaging.

bioRxiv · Nov 17, 2021 · PreprintBioengineering

Stag1 and Stag2 regulate cell fate decisions in hematopoiesis through non-redundant topological control

A. D. Viny, R. L. Bowman, Y. Liu, V.-P. Lavallee, S. E. Redlich, W. Xiao, B. H. Durham, A. Navitski, J. Park, S. Braunstein, E. Azizi, M. Witkin, T. Baslan, C. J. Ott, D. Pe'er, , R. L. Levine

The paper shows Stag2 loss in HSPCs impairs B-cell lineage commitment by reducing chromatin accessibility, while Stag1 cannot restore this function despite rescuing topological domains.

bioRxiv · Mar 18, 2019 · PreprintCell Biology

Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment

E. Azizi, A. J. Carr, G. Plitas, A. E. Cornish, C. Konopacki, S. Prabhakaran, J. Nainys, K. Wu, V. Kiseliovas, M. Setty, K. Choi, R. M. Fromme, P. Dao, P. T. McKenney, R. C. Wasti, , D. Pe'er

The paper maps immune cell phenotypes in breast cancer using single-cell RNA-seq and identifies continuous tumor-specific expansions driven by environmental cues.

bioRxiv · Apr 2, 2018Immunology