Molecular BiologybioRxivPreprint
TLR5 drives metabolic dysfunction-associated steatohepatitis through lipid- and flagellin-induced hepatocyte injury signalling
W. Li, N. Wang, R. Kumar…·W. Alazawi
The paper investigates TLR5's role in MASH and fibrosis using clinical data, single-cell transcriptomics, and in vitro models, finding TLR5 drives hepatocyte injury and fibrosis through flagellin and lipid pathways.
DOI 10.64898/2026.02.05.703969