M. K. Andersen

Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells

The paper identifies club-like cells in the prostate tumor microenvironment that contribute to androgen deprivation therapy resistance through immune suppression.

The freeze-avoiding mountain pine beetle (Dendroctonus ponderosae) survives prolonged exposure to stressful cold by mitigating ionoregulatory collapse

This study examines how mountain pine beetle larvae maintain ion balance during cold exposure and finds that ionoregulatory collapse limits their cold tolerance.

Tropical butterflies lose central nervous system function in the cold from a spreading depolarization event

This study shows that cold exposure induces spreading depolarization in butterfly brains, leading to loss of central nervous system function and supporting its role in the critical thermal minimum across insects.

Plasticity in Na+/K+-ATPase thermal kinetics drives variation in the critical thermal minimum of adult Drosophila melanogaster

This study shows that cold acclimation in Drosophila melanogaster lowers the critical thermal minimum by reducing Na+/K+-ATPase sensitivity to temperature, without changing pump abundance.

Elemental stoichiometry and insect chill tolerance: Evolved and plastic changes in organismal Na+ and K+ content in Drosophila

This study examines how acclimation and adaptation affect chill tolerance and elemental stoichiometry in Drosophila, finding acclimation has a greater impact than adaptation.

Thermal acclimation alters the roles of Na+/K+-ATPase activity in a tissue-specific manner in Drosophila melanogaster

This study examines how cold acclimation affects Na+/K+-ATPase activity in different tissues of Drosophila melanogaster, showing tissue-specific changes in thermal sensitivity and activity that relate to cold tolerance.

Hyperkalemia, not apoptosis, accurately predicts insect chilling injury

This study investigates the mechanism of chilling injury in locusts and finds that hyperkalemia, not apoptosis, is the key predictor of injury severity.

Inter- and intraspecific differences in Drosophila cold tolerance are linked to hindgut reabsorption capacity

This study investigates how cold tolerance in Drosophila is linked to hindgut reabsorption capacity, finding that cold-adapted species maintain better ion and fluid reabsorption at low temperatures.

Cholesterol Synthesis Pathway Genes in Prostate Cancer are consistently downregulated when tissue confounding is minimized.

This study shows that minimizing tissue confounding reveals consistent downregulation of cholesterol synthesis pathway genes in prostate cancer.