BiochemistrybioRxiv
Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains
M. Myllykoski, A. Sutinen, M. K. Koski…·P. Koivunen
The paper determines the 3D structure of human P4H-TM using X-ray crystallography, revealing structural features and Ca2+ binding properties relevant to its catalytic activity and association with HIDEA syndrome.
DOI 10.1074/jbc.ra120.016542