Author

M. Kirkpatrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 8

Signature Assays, Organisms & Methods

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Approach:statistical model· 7 Organism:bacteria (other)· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. Harpak· 2 shared B. J. Pinto· 2 shared C. Cheng· 2 shared C. H. Smith· 2 shared J. C. Havird· 2 shared M. J. Ming· 2 shared A. A. Hoffmann· 1 shared A. C. Dalziel· 1 shared

Activity by Year

2016-2024 · peak 3/yr

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10 top collaborators · 9 mutual co-author links

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2 shared papersEvolutionary Biology

A. Harpak

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8 papers

Recent·Most cited

Does Sex-Differential Gene Expression Drive Sex-Differential Selection in Humans?

M. J. Ming, C. Cheng, M. Kirkpatrick, A. Harpak

The paper challenges the hypothesis that sex-differential gene expression drives sex-differential selection by showing no genome-wide relationship between sex differences in expression and selection on eQTLs across 39 human tissues.

bioRxiv · Jul 23, 2024 · PreprintEvolutionary Biology

The battle of the sexes in humans is highly polygenic

J. M. Cole, C. B. Scott, M. M. Johnson, P. R. Golightly, J. Carlson, M. J. Ming, A. Harpak, M. Kirkpatrick

This study quantifies sex-differential selection (SDS) across the human genome using UK Biobank data, revealing polygenic signals and a tradeoff between viability and fecundity.

bioRxiv · Jul 23, 2024Evolutionary Biology

Bacterial ecology and evolution converge on seasonal and decadal scales

R. R. Rohwer, M. Kirkpatrick, S. L. Garcia, M. Kellom, K. D. McMahon, B. J. Baker

The paper analyzes a two-decade freshwater lake metagenome dataset to show that ecological and evolutionary processes in microbial communities operate on seasonal and decadal scales.

bioRxiv · Feb 6, 2024Evolutionary Biology

Mitonuclear sex determination? Empirical evidence frombivalves

C. H. Smith, R. Mejia-Trujillo, S. H. Breton, B. J. Pinto, M. Kirkpatrick, J. C. Havird

This study investigates the role of mitochondrial and nuclear genes in sex determination in bivalves, finding that male mtDNA sncRNAs inhibit female development while nuclear factors remain inconclusive.

bioRxiv · Jul 5, 2023Evolutionary Biology

How many ecological niches are defined by the superabundant marine microbe Prochlorococcus?

M. Miyagi, M. Morrison, M. Kirkpatrick

The paper introduces a tree-free likelihood method to identify ecotypes in Prochlorococcus and finds 24 ecotypes in 96 genomes, more than the commonly recognized five.

bioRxiv · Nov 29, 2022 · PreprintEvolutionary Biology

A tale of two paths: The evolution of mitochondrial recombination in bivalves with doubly uniparental inheritance

C. H. Smith, B. J. Pinto, M. Kirkpatrick, D. M. Hillis, J. M. Pfeiffer, J. C. Havird

This study investigates mitochondrial recombination in bivalves with doubly uniparental inheritance, finding evidence for a single origin of male mitochondrial DNA and ongoing recombination in some species.

bioRxiv · Oct 22, 2022Evolutionary Biology

Contrasting tempos of sex chromosome degeneration in sticklebacks

J. M. Sardell, M. P. Josephson, A. C. Dalziel, C. L. Peichel, M. Kirkpatrick

This study compares sex chromosome evolution in three stickleback species, finding that blackspotted sticklebacks show more extensive recombination suppression and Y degeneration than their relatives.

bioRxiv · Sep 17, 2020 · PreprintEvolutionary Biology

Extensive genetic differentiation between homomorphic sex chromosomes in the mosquito vector, Aedes aegypti

A. Fontaine, I. Filipovic, T. Fansiri, A. A. Hoffmann, C. Cheng, M. Kirkpatrick, G. Rasic, L. Lambrechts

The paper shows that sex chromosomes in Aedes aegypti are genetically differentiated over a large region, not just a small sex-determining region, and demonstrates how this can be used for accurate sex assignment and population genomic studies.

bioRxiv · Jun 21, 2016Evolutionary Biology