J. Carlson

JGI Plant Gene Atlas: An updateable transcriptome resource to improve structural annotations and functional gene descriptions across the plant kingdom

The paper introduces the JGI Plant Gene Atlas, a resource that improves gene function annotations by analyzing transcript abundance across 18 species and 604 tissues, identifying 64,620 genes with unknown functions.

Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in an ovarian carcinoma model

This study evaluates anti-SSEA-4 CAR-T cells in ovarian cancer models, showing efficacy against SSEA-4 positive cells but highlighting dose-dependent toxicity.

Drosophila Keap1 oxidative/xenobiotic response factor interacts with B-type lamin to regulate nuclear lamina and heterochromatin

This study shows that dKeap1 interacts with lamin Dm0 to regulate nuclear lamina and heterochromatin, linking the Keap1-Nrf2 pathway to chromatin structure and developmental transcription.

The apportionment of citations: A scientometric analysis of Lewontin, 1972

This paper analyzes the citation trajectory of Lewontin's 1972 study on human genetic diversity, identifying factors contributing to its enduring influence and examining its role in contemporary discussions about race and genetics.

Host genomic influence on bacterial composition in the switchgrass rhizosphere

This study investigates how switchgrass genotypes influence rhizosphere bacterial composition and diversity, finding genetic associations and heritability in bacterial communities.

Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates

The paper evaluates variation in germline mutation rate estimates across labs using a standardized pedigree of rhesus macaques, highlighting methodological differences and the need for standardization.

Differential taphonomic effects of petroleum seeps and karstic sinkholes on ancient dire wolf teeth: Hydrocarbon impregnation preserves fossils for chemical and histological analysis

This study compares the preservation of dire wolf teeth from petroleum seeps and karstic sinkholes, finding that seep environments better preserve dental microstructure for chemical and histological analysis.

Quantifying and contextualizing the impact of bioRxiv preprints through social media audience segmentation

This study analyzes Twitter engagement with bioRxiv preprints to identify audience segments, revealing that most are academic, but some have significant right-wing nationalist engagement.

Spatiotemporal single-cell profiling of gastrointestinal GVHD reveals invasive and resident memory T cell states.

The paper uses SIVS and scRNA-seq to analyze T cell infiltration and residency in the GI tract during aGVHD, identifying genes associated with tissue invasiveness and TRM programming.

A community-maintained standard library of population genetic models

The paper introduces stdpopsim, a community-maintained library for population genetic models, to standardize simulations and facilitate benchmarking of inference tools.