Author

A. Fontaine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Ecology· 2 Bioengineering· 1 Cell Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Organism:Arabidopsis· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

L. Lambrechts· 3 shared S. Lequime· 3 shared A. Baidaliuk· 2 shared C. de Lombares· 2 shared G. Alfama· 2 shared G. Levi· 2 shared N. Narboux-Neme· 2 shared S. Briolant· 2 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

L. Lambrechts

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Author profile →

11 papers

Recent·Most cited

Sand flies and Toscana virus: intra-vector infection dynamics and impact on Phlebotomus perniciosus life-history traits

L. Laroche, A.-L. Banuls, R. Charrel, A. Fontaine, N. Ayhan, J. Prudhomme

This study investigates TOSV infection dynamics in Phlebotomus perniciosus sand flies and finds it affects their life history traits, including hatching time and extrinsic incubation period.

bioRxiv · Feb 25, 2024 · PreprintMicrobiology

Vascular damage and excessive proliferation compromise liver function after extended hepatectomy in mice

M. De Rudder, R. Manco, L. Coubeau, A. Fontaine, C. Bertrand, I. Leclercq, A. Dili

The study shows that combining G-CSF and HNF4 overexpression rescues vascular damage and improves survival after extended hepatectomy in mice.

bioRxiv · Jan 4, 2024Cell Biology

Combining two Genetic Sexing Strains allows sorting of non-transgenic males for Aedes genetic control

C. Lutrat, M. Burckbuchler, R. P. Olmo, R. Beugnon, A. Fontaine, O. S. Akbari, R. Argiles-Herrero, T. Baldet, J. Bouyer, E. Marois

This paper presents Genetic Sexing Strains for Aedes mosquitoes that enable efficient sorting of non-transgenic males for genetic control.

bioRxiv · Mar 11, 2022 · PreprintBioengineering

Mosquito excreta reveals circulation of West Nile virus and its underlying ecosystem

G. L Ambert, M. Gendrot, S. Briolant, A. Nguyen, S. Pages, L. Bosio, V. Palomo, N. Gomez, N. Benoit, H. Savini, B. Pradines, G. A. Durand, I. Leparc-Goffart, G. Grard, A. Fontaine

The paper identifies West Nile Virus circulation in Camargue using mosquito excreta-based xenomonitoring and reveals ecological networks of arbovirus transmission.

bioRxiv · Dec 5, 2021 · PreprintEcology

High transmissibility and fetal pathogenicity of recent Zika virus strains from the African lineage

F. Aubry, S. Jacobs, M. Darmuzey, S. Lequime, L. Delang, A. Fontaine, N. Jupatanakul, E. F. Miot, S. Dabo, C. Manet, X. Montagutelli, A. Baidaliuk, F. Gambaro, E. Simon-Loriere, M. Gilsoul, , L. Lambrechts

This study compares transmissibility and pathogenicity of recent African and Asian Zika virus strains, finding African strains more transmissible, lethal, and capable of causing fetal death.

bioRxiv · Sep 1, 2020Microbiology

Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries

Y. Suzuki, A. Baidaliuk, P. Miesen, L. Frangeul, A. B. Crist, S. H. Merkling, A. Fontaine, S. Lequime, I. Moltini-Conclois, H. Blanc, R. P. van Rij, L. Lambrechts, M.-C. Saleh

The paper shows that a non-retroviral EVE in Aedes aegypti limits replication of its cognate virus, CFAV, through piRNA-mediated antiviral activity in ovaries.

bioRxiv · Mar 28, 2020Microbiology

A mosquito survey along a transect of urbanization in Dschang, West Region of Cameroon, reveals potential risk of arbovirus spillovers

M. P. A. Mayi, R. Bamou, B. Djiappi-Tchamen, C. Djojo-Tachegoum, A. Fontaine, C. Antonio-Nkondjio, T. Tchuinkam

A mosquito survey in Cameroon's Dschang area identifies species potentially involved in arbovirus spillover from sylvatic to urban environments.

bioRxiv · Sep 23, 2019 · PreprintEcology

European and tropical Aedes albopictus mosquito populations have similar systemic Zika virus infection dynamics

S. Lequime, J.-S. Dehecq, S. Briolant, A. Fontaine

This study shows that European and tropical Aedes albopictus populations have similar systemic Zika virus infection dynamics, suggesting potential for autochthonous transmission.

bioRxiv · Sep 10, 2019 · PreprintMicrobiology

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan.

C. de Lombares, E. Heude, G. Alfama, A. Fontaine, R. Hassouna, C. Vernochet, F. de Chaumont, J.-C. Olivo-Marin, E. Ey, S. Parnaudeau, F. Tronche, T. Bourgeron, S. Luquet, G. Levi, N. Narboux-Neme

This study shows that Dlx5 and Dlx6 in GABAergic neurons affect behavior, metabolism, aging, and lifespan in mice.

bioRxiv · Mar 20, 2019Physiology

Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain

B. Bellessort, A. Bachelot, V. Grouthier, C. De Lombares, N. Narboux-Neme, P. Garagnani, C. Pirazzini, S. Astigiano, L. Mastracci, A. Fontaine, G. Alfama, E. Duvernois-Berthet, G. Levi

The paper identifies CACNA2D1, CACNA2D2, and CACNA2D3 as potential targets for gabapentin in treating endometriosis-associated pain through comparative gene expression analysis.

bioRxiv · Jan 22, 2018Pharmacology & Toxicology

Extensive genetic differentiation between homomorphic sex chromosomes in the mosquito vector, Aedes aegypti

A. Fontaine, I. Filipovic, T. Fansiri, A. A. Hoffmann, C. Cheng, M. Kirkpatrick, G. Rasic, L. Lambrechts

The paper shows that sex chromosomes in Aedes aegypti are genetically differentiated over a large region, not just a small sex-determining region, and demonstrates how this can be used for accurate sex assignment and population genomic studies.

bioRxiv · Jun 21, 2016Evolutionary Biology