Proteome and functional decline as platelets age in the circulation
H. E. Allan, M. A. Hayman, S. Marcone, M. V. Chan, M. L. Edin, T. Maffucci, A. Joshi, L. Menke, M. Crescente, M. Mayr, D. C. Zeldin, P. C. Armstrong, T. D. Warner
The paper investigates age-related changes in platelets, finding reduced protein content, altered proteomic pathways, and functional decline in older platelets.
bioRxiv · Jun 2, 2021Cell Biology