Author

T. D. Warner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

H. E. Allan· 4 shared M. Crescente· 3 shared P. C. Armstrong· 3 shared A. Joshi· 2 shared M. Mayr· 2 shared A. Cappelletto· 1 shared A. Vadgama· 1 shared C. A. Mein· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

H. E. Allan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multi-parameter phenotyping of platelets and characterisation of the effects of agonists using machine learning

A. Vadgama, J. Boot, H. E. Allan, C. A. Mein, P. C. Armstrong, T. D. Warner

This paper uses multi-parameter flow cytometry and machine learning to characterize platelet sub-populations and their responses to agonists, achieving high accuracy in distinguishing platelet age and activation states.

bioRxiv · Dec 8, 2023Immunology

Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

P. C. Armstrong, H. E. Allan, N. S. Kirkby, A. Joshi, C. Gutmann, M. Crescente, J. A. Mitchell, M. Mayr, T. D. Warner

This study uses in vivo temporal labeling to show age-dependent changes in mouse platelet function and mRNA conservation.

bioRxiv · Dec 17, 2021Physiology

SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

A. Cappelletto, H. E. Allan, M. Crescente, E. Schneider, R. Bussani, H. Ali, I. Secco, S. Vodret, R. Simeone, L. Mascaretti, S. Zacchigna, T. D. Warner, M. Giacca

This paper shows that SARS-CoV-2 Spike protein activates TMEM16F in platelets, enhancing pro-coagulant activity and thrombosis, which is inhibited by Niclosamide and Clofazimine.

bioRxiv · Dec 14, 2021 · PreprintPathology

Proteome and functional decline as platelets age in the circulation

H. E. Allan, M. A. Hayman, S. Marcone, M. V. Chan, M. L. Edin, T. Maffucci, A. Joshi, L. Menke, M. Crescente, M. Mayr, D. C. Zeldin, P. C. Armstrong, T. D. Warner

The paper investigates age-related changes in platelets, finding reduced protein content, altered proteomic pathways, and functional decline in older platelets.

bioRxiv · Jun 2, 2021Cell Biology