Author

M. Mayr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

X. Yin· 3 shared A. Joshi· 2 shared H. E. Allan· 2 shared M. Crescente· 2 shared P. C. Armstrong· 2 shared T. D. Warner· 2 shared A. El-Armouche· 1 shared A. L. Fellows· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

X. Yin

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

ARF6 as a novel activator of HIF-2alpha in pulmonary arterial hypertension

A. L. Fellows, C.-N. Chen, C. Xie, N. Iyer, L. Schmidt, X. Yin, M. Mayr, A. S. Cowburn, L. Zhao, B. Wojciak-Stothard

This study identifies ARF6 as a novel activator of HIF-2alpha in pulmonary arterial hypertension and shows that the antibiotic CTC inhibits this pathway.

bioRxiv · Sep 15, 2023Cell Biology

Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

S. G. Romeo, I. Secco, E. Schneider, C. M. Reumiller, C. X. Santos, A. Pooni, X. Yin, K. Theofilatos, S. Cellone Trevelin, L. Zeng, G. E. Mann, A. Margariti, M. Mayr, A. M. Shah, M. Giacca, A. Zampetaki

This study uses human blood vessel organoids to show that CTGF is critical for maintaining microvascular integrity under metabolic stress.

bioRxiv · Sep 1, 2022Cell Biology

Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

P. C. Armstrong, H. E. Allan, N. S. Kirkby, A. Joshi, C. Gutmann, M. Crescente, J. A. Mitchell, M. Mayr, T. D. Warner

This study uses in vivo temporal labeling to show age-dependent changes in mouse platelet function and mRNA conservation.

bioRxiv · Dec 17, 2021Physiology

Proteome and functional decline as platelets age in the circulation

H. E. Allan, M. A. Hayman, S. Marcone, M. V. Chan, M. L. Edin, T. Maffucci, A. Joshi, L. Menke, M. Crescente, M. Mayr, D. C. Zeldin, P. C. Armstrong, T. D. Warner

The paper investigates age-related changes in platelets, finding reduced protein content, altered proteomic pathways, and functional decline in older platelets.

bioRxiv · Jun 2, 2021Cell Biology

Structural Insights on Fusion Mechanisms of Extracellular Vesicles with Model Plasma Membrane

F. Perissinotto, V. M. Rondelli, B. Senigagliesi, P. Brocca, L. Almasy, L. Bottyan, D. G. Merkel, B. Sartori, H. Amenitsch, K. Pachler, M. Mayr, M. Gimona, E. Rohde, L. Casalis, P. Parisse

This study uses physical techniques to investigate how extracellular vesicles interact with model membranes, revealing their preference for lipid raft domains and shedding light on uptake mechanisms.

Nanoscale · Jan 1, 2021Peer-reviewedBiophysics

Hypoxia-induced epigenetic silencing of polo-like kinase 2 promotes fibrosis in atrial fibrillation

S. R. Kuenzel, K. Sekeres, S. Kaemmerer, T. Kolanowski, S. Meyer-Roxlau, C. Piorkowski, S. M. Tugtekin, S. Rose-John, X. Yin, M. Mayr, J. D. Kuhlmann, P. Wimberger, K. Gruetzmann, N. Herzog, J.-H. Kuepper, , A. El-Armouche

This study identifies hypoxia-induced epigenetic silencing of PLK2 and its role in promoting atrial fibrosis via OPN secretion in AF.

bioRxiv · Oct 17, 2018Pharmacology & Toxicology