BiochemistrybioRxiv
Exaptation of two ancient immune proteins into a new dimeric pore-forming toxin in snails
M. L. Giglio, S. Ituarte, V. Milesi…·H. Heras
This paper presents the structure of PmPV2, a MACPF toxin from snail eggs, showing it forms pores in target membranes through a novel dimeric mechanism.
DOI 10.1016/j.jsb.2020.107531