Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species
M. Essaidi-Laziosi, F. J. Perez Rodriguez, C. Alvarez, P. Sattonnet-Roche, G. Torriani, M. Bekliz, K. Adea, M. Lenk, W. Preiser, T. Suliman, M. A. Muller, C. Drosten, L. Kaiser, I. Eckerle
The paper compares the replicative capacity of SARS-CoV-2 variants in human primary cells and mammalian cell lines, finding Omicron BA.1 has a distinct phenotype in human nasal epithelia but no increased host range in other species.
bioRxiv · Oct 4, 2022Microbiology