C. Alvarez

Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1

This study evaluates immune escape and replicative capacity of Omicron variants in human airway epithelial cells and sera from diverse immunological backgrounds.

Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species

The paper compares the replicative capacity of SARS-CoV-2 variants in human primary cells and mammalian cell lines, finding Omicron BA.1 has a distinct phenotype in human nasal epithelia but no increased host range in other species.

Online μSEC2-nRPLC-MS for improved sensitivity of intact protein detection of IEF separated non-human primate cerebrospinal fluid proteins

The paper introduces an online SEC2-nRPLC-MS platform to enhance intact protein detection in complex samples, achieving higher sensitivity and coverage in non-human primate cerebrospinal fluid.

Early events of the endophytic symbiotic between Oryza sativa and Nostoc punctiforme involve the SYM pathway

The paper identifies early molecular events in the symbiosis between Oryza sativa and Nostoc punctiforme, showing activation of the SYM pathway in both partners.

Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo

The paper identifies a minimal code in the Go subunit N-terminus that governs its localization to the plasma membrane and Golgi, independent of transport, and introduces an assay to study PAT substrate specificity.

SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species

This study compares SARS-CoV-2 infection in three nonhuman primate species, showing varied disease progression and immune responses.

Modulating Sphingosine-1-Phosphate receptors to improve chemotherapy delivery to Ewing sarcoma

This study shows that modulating S1PR1 and S1PR2 improves chemotherapy delivery and efficacy in Ewing sarcoma by normalizing tumor vessel permeability.