Author

M. Lihan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

E. Tajkhorshid· 2 shared A. Arango· 1 shared D. Gorgun· 1 shared D. Lupyan· 1 shared D. Oehme· 1 shared J. L. Jenkins· 1 shared K. Kapoor· 1 shared L. R. Hurst· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

E. Tajkhorshid

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Target-template relationships in protein structure prediction and their effect on the accuracy of thermostability calculations

D. Oehme, M. Lihan, D. Lupyan

This study evaluates FEP+'s accuracy in predicting protein thermostability using homology models, finding that local sequence conservation improves prediction performance.

bioRxiv · Sep 19, 2022Biophysics

Binding Mode of SARS-CoV2 Fusion Peptide to Human Cellular Membrane

D. Gorgun, M. Lihan, K. Kapoor, E. Tajkhorshid

This study uses molecular dynamics simulations to analyze how the SARS-CoV2 fusion peptide binds to human cell membranes, identifying three binding modes with the deepest penetration being the most biologically relevant.

bioRxiv · Oct 27, 2020Biophysics

Phosphatidic acid inhibits SNARE priming by inducing conformational changes in Sec18 protomers

M. L. Starr, R. A. Sparks, L. R. Hurst, Z. Zhao, A. Arango, M. Lihan, J. L. Jenkins, E. Tajkhorshid, R. A. Fratti

This study shows phosphatidic acid (PA) inhibits SNARE priming by altering Sec18 conformation and stabilizing membrane-bound protomers.

bioRxiv · Jul 9, 2018Biochemistry