Cancer BiologybioRxiv
Cancer Associated Fibroblasts Mediate Cancer Progression and Remodel the Tumouroid Stroma
J. Pape, T. Magdeldin, K. Stamati…·U. Cheema
This study shows that cancer-associated fibroblasts (CAFs) enhance cancer invasion and remodeling in a 3D in vitro model by upregulating specific factors and disrupting vascular networks.
DOI 10.1038/s41416-020-0973-9