Author

U. Cheema

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. Loizidou· 2 shared S. Heavey· 2 shared A. Nam· 1 shared A. Nyga· 1 shared C. Moore· 1 shared D. Bakkalci· 1 shared D. Tandon· 1 shared G. Al-Badri· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. Loizidou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.

Z. Ahmed, W. Mosabbir, D. Tandon, S. P. Pereira, U. Cheema, M. Loizidou, J. Withington, C. Moore, U. Okoli, S. Heavey

This study evaluates the clinical relevance of prostate cancer cell lines by comparing them to human patient data and multiomics profiles, finding they represent a small fraction of patients and recommending a tailored selection pipeline.

bioRxiv · Mar 20, 2024 · PreprintCancer Biology

Spatial transcriptome profiling of in vitro 3D tumouroids to study tumour-stroma interactions

D. Bakkalci, G. Al-Badri, W. Yang, A. Nam, Y. Ling, S. A. Khurram, S. Heavey, S. Fedele, U. Cheema

This study uses spatial transcriptomics to analyze how different stromal cells affect gene expression and behavior in engineered ameloblastoma tumouroids.

bioRxiv · Dec 13, 2022 · PreprintBioengineering

Cancer Associated Fibroblasts Mediate Cancer Progression and Remodel the Tumouroid Stroma

J. Pape, T. Magdeldin, K. Stamati, A. Nyga, M. Loizidou, M. Emberton, U. Cheema

This study shows that cancer-associated fibroblasts (CAFs) enhance cancer invasion and remodeling in a 3D in vitro model by upregulating specific factors and disrupting vascular networks.

bioRxiv · Nov 29, 2019Cancer Biology