Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
K. Kumpornsin, T. Kochakarn, T. Yeo, M. Luth, R. D. Pearson, J. Hoshizaki, K. Schindler, S. Mok, H. Park, A.-C. Uhlemann, S. M. Cubel, V. Franco, M. Gomez-Lorenzo, F.-J. Gamo, E. Winzeler, , M. C. Lee
This study creates a mutator parasite of Plasmodium falciparum to enhance drug resistance discovery by increasing mutation rates and identifying resistance mechanisms.
bioRxiv · Aug 23, 2022 · PreprintMicrobiology