Author

E. Winzeler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Churchyard· 1 shared A. K. Lawong· 1 shared A. Kumar· 1 shared A. Rozenberg· 1 shared A.-C. Uhlemann· 1 shared B. Crespo-Fernandez· 1 shared B. Laleu· 1 shared B. Posner· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. Churchyard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A fast-killing tyrosine amide ((S)-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus (PfCARL)

L. S. Imlay, A. K. Lawong, S. Gahalawat, A. Kumar, C. Xing, N. Mittal, S. Wittlin, A. Churchyard, H. Niederstrasser, B. Crespo-Fernandez, B. Posner, F.-J. S. Gamo, J. Baum, E. Winzeler, B. Laleu, , M. A. Phillips

This paper identifies (S)-SW228703, a tyrosine amide with fast-killing antimalarial activity against blood and liver stages of Plasmodium falciparum, and links resistance to mutations in PfCARL and PfACT.

bioRxiv · Oct 16, 2022Microbiology

Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

K. Kumpornsin, T. Kochakarn, T. Yeo, M. Luth, R. D. Pearson, J. Hoshizaki, K. Schindler, S. Mok, H. Park, A.-C. Uhlemann, S. M. Cubel, V. Franco, M. Gomez-Lorenzo, F.-J. Gamo, E. Winzeler, , M. C. Lee

This study creates a mutator parasite of Plasmodium falciparum to enhance drug resistance discovery by increasing mutation rates and identifying resistance mechanisms.

bioRxiv · Aug 23, 2022 · PreprintMicrobiology

Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in Toxoplasma gondii.

A. Rozenberg, M. R. Luth, M. Behnke, E. Winzeler, L. D. Sibley

This study identifies novel mutations in Toxoplasma gondii that confer resistance to artemisinin, including mitochondrial genome amplification and changes in mitochondrial function.

Proceedings of the National Academy of Sciences · Dec 5, 2019Peer-reviewedMicrobiology