Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles
C. Specht, E. J. Homan, C. K. Lee, Z. Mou, C. L. Gomez, M. M. Hester, A. Abraham, F. Rus, G. Ostroff, S. M. Levitz
The paper shows that glucan particle-based vaccines containing specific peptides from C. neoformans proteins can protect mice against cryptococcosis, with varying efficacy depending on the peptide and mouse strain.
bioRxiv · Nov 12, 2021Immunology