Author

F. Rus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Abraham· 3 shared D. Gazzola· 2 shared E. Soto· 2 shared G. Ostroff· 2 shared H. Li· 2 shared J. F. Urban· 2 shared K. Flanagan· 2 shared R. V. Aroian· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

A. Abraham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Purified cytosolic crystals from Bacillus thuringiensis as a novel active pharmaceutical ingredient (API)

J. Chicca, N. R. Cazeault, F. Rus, A. Abraham, C. Garceau, H. Li, S. M. Atwa, K. Flanagan, E. Soto, M. S. Morrison, D. Gazzola, Y. Hu, D. R. Liu, M. K. Nielsen, J. F. Urban, , R. V. Aroian

This paper describes the scalable purification of Bt Cry5B crystals and demonstrates their potent bioactivity against nematodes in vitro and in vivo.

bioRxiv · May 20, 2022 · PreprintMicrobiology

Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles

C. Specht, E. J. Homan, C. K. Lee, Z. Mou, C. L. Gomez, M. M. Hester, A. Abraham, F. Rus, G. Ostroff, S. M. Levitz

The paper shows that glucan particle-based vaccines containing specific peptides from C. neoformans proteins can protect mice against cryptococcosis, with varying efficacy depending on the peptide and mouse strain.

bioRxiv · Nov 12, 2021Immunology

Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans

H. Li, A. Abraham, D. Gazzola, Y. Hu, G. Beamer, K. Flanagan, E. Soto, F. Rus, Z. Mirza, A. Draper, S. Vakalapudi, C. Stockman, P. Bain, J. F. Urban, G. R. Ostroff, R. V. Aroian

This paper develops a safe, effective, and scalable anthelmintic based on Bacillus thuringiensis Cry5B for treating human gastrointestinal nematodes.

bioRxiv · Sep 2, 2020Microbiology