ImmunologybioRxiv
B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism
E. E. Irons, M. M. Lee-Sundlov, K. M. Hoffmeister, J. T. Y. Lau
This study shows B cells suppress granulopoiesis by modifying sialylation on hematopoietic progenitors via ST6Gal-1, with implications for myeloma and neutrophil abundance.
DOI 10.7554/elife.47328