BioengineeringbioRxiv
Emergent collective organization of bone cells in complex curvature fields
S. J. P. Callens, D. Fan, I. A. J. van Hengel…·A. A. Zadpoor
This study shows micro-engineered substrates with curvature variations induce collective spatiotemporal organization of preosteoblasts, revealing curvature-guided cell behavior and mechanical regulation.
DOI 10.1038/s41467-023-36436-w