BiochemistrybioRxiv
The Molecular Basis of Specific DNA Binding by the BRG1 AT-hook and Bromodomain
J. C. Sanchez, L. Zhang, S. Evoli…·C. A. Musselman
This study identifies the DNA specificity and structural basis of BRG1's composite domain using SELEX-seq, NMR, and modeling, showing how cancer mutations alter DNA binding.
DOI 10.1016/j.bbagrm.2020.194566