mRNA vaccine induces protective immunity against the type III secretory virulence of Pseudomonas aeruginosa
K. Kawaguchi, M. Kinoshita, K. Sudo, K. Inoue, Y. Naito, M. Oba, S. Uchida, T. Sawa
This study develops an mRNA vaccine targeting Pseudomonas aeruginosa's type III secretion system, showing improved mouse survival and reduced lung bacterial load after challenge.
bioRxiv · Jun 9, 2023 · PreprintImmunology