Transient induction of cell cycle promoter Fam64a improves cardiac function through regulating Klf15-dependent cardiomyocyte differentiation in mice
K. Hashimoto, A. Kodama, M. Ohira, M. Kimoto, R. Nakagawa, Y. Usui, Y. Ujihara, A. Hanashima, S. Mohri
This study shows that transient activation of Fam64a improves cardiac function in adult mice by promoting cardiomyocyte proliferation without excessive dedifferentiation.
bioRxiv · Apr 1, 2021 · PreprintPhysiology