BiophysicsbioRxiv
Allosteric Regulation of the EphA2 Receptor Intracellular Region by Serine/Threonine Kinases
B. C. Lechtenberg, M. P. Gehring, T. P. Light…·E. B. Pasquale
This study reveals two allosteric mechanisms by which serine/threonine phosphorylation of the EphA2 linker regulates its non-canonical signaling, providing insights into its role in cancer.
DOI 10.1038/s41467-021-27343-z