Modeling flexible protein structure with AlphaFold2 and cross-linking mass spectrometry
K. Manalastas-Cantos, K. R. Adoni, M. Pfeifer, B. Maertens, K. Grunewald, K. Thalassinos, M. Topf
The paper introduces a pipeline combining AlphaFold2 and XL-MS to model protein conformations, showing improved accuracy in identifying correct structures using new scores.
bioRxiv · Sep 11, 2023Biochemistry