J. Hiblot

The paper develops a biosensor, iAspSnFR, to measure intracellular aspartate levels in live cells and demonstrates its utility in studying metabolic pathways and cancer biology.

The paper introduces a method to create multicolor biosensors with large dynamic ranges using FRET pairs based on fluorescent proteins and HaloTag.

This paper demonstrates 6-target STED microscopy using exchangeable labels, improving multiplexing capabilities and reducing photobleaching in live-cell imaging.

The paper introduces exchangeable HaloTag ligands for multi-modal super-resolution fluorescence microscopy, enabling dual-color imaging techniques like PAINT and STED.

The paper identifies a new Inovirus, RIP1, in the human virome without bacterial infection, showing its presence in multiple body sites.

The paper demonstrates that eight pairwise combinations of 18 synthetic fluorescent probes are suitable for fluorescence lifetime multiplexing in mammalian cells, enabling imaging of up to six biological targets.

HaloTag9 improves fluorophore performance with higher brightness and fluorescence lifetime, enabling live-cell multiplexing and biosensor generation.

The paper compares the labeling kinetics and substrate specificities of HaloTag7, SNAP-tag, and CLIP-tag to guide their optimal use in bioimaging and biotechnology.